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ghosttent wrote 27 articles and got 0 comments. The last article was submitted on 16/11/18

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Find High Quality alpha-Arbutin (84380-01-8) from LEAPChem!

Date 09/11/18 05:20 Views 5 Сomments 0

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Find High Quality alpha-Arbutin (84380-01-8) from LEAPChem!
At LEAPChem - Pharmaceutical Chemicals, we proudly supply the materials that are required for the wide range of our customers’ production processes. We understand that each production process is unique, which is why we provide custom services and chemical knowledge tailored to each customer specifically. With LEAPChem, you can look forward to receiving the operational benefits of working with an international company paired with the customer service and reliable follow up of a small business. LEAPChem Highlights alpha-Arbutin today!

Basic Information of alpha-Arbutin
Chemical Name: alpha-Arbutin
Cas No.: 84380-01-8
Molecular Formula: C12H16O7
Chemical Structure:


Arbutin is a glycoside; a glycosylated hydroquinone extracted from the bearberry plant in the genus Arctostaphylos among many other medicinal plants, primarily in the Ericaceae family. Applied topically, it inhibits tyrosinase and thus prevents the formation of melanin. Arbutin is therefore used as a skin-lightening agent. Very tiny amounts of arbutin are found in wheat, pear skins, and some other foods. It is also found in Bergenia crassifolia. Arbutin was also produced by an in vitro culture of Schisandra chinensis.
It works by slowly releasing hydroquinone through hydrolysis, which in turn blocks Tyrosinase activity and reduces the skin’s melanin (pigmentation) production. In cosmetics, this ingredient appears in two different forms: Alpha-Arbutin or Beta-Arbutin. Due to patenting concerns, most skin care products contain plant extracts that contain Arbutin (e.g. bearberry, pear, blueberry), rather than pure Arbutin. Used in a variety of cosmetics, particularly ones aimed at lightening the skin such as lotions, crèmes, serums, cleansers, and spot treatments.
Bearberry extract is used in skin lightening treatments designed for long term and regular use. An active agent in brands of skin lightening preparations, it is more expensive than traditional skin lightening ingredients like hydroquinone, which is now banned in many countries. In vitro studies of human melanocytes exposed to arbutin at concentrations below 300 μg/mL reported decreased tyrosinase activity and melanin content with little evidence of cytotoxicity.

As an industry leader in chemical sourcing, LEAPChem has strong relationships with vendors, suppliers, and customers worldwide that allow us to access hard to find chemicals at competitive prices. Our warehouses are equipped to handle kosher, organic, hazardous, and non-hazardous materials. We have established partnerships with import and export providers making seamless international shipping possible.

If you are interested in alpha-Arbutin, click here to send an inquiry!
Make LEAPChem your pharmaceutical chemicals long-term partner and contact us today!

References:
en.wikipedia.org
www.ncbi.nlm.nih.gov
www.ncbi.nlm.nih.gov

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